 | From the Editor's Desk
Evidence-based, Cost-effective Interventions to Suppress the COVID-19 Pandemic: a Rapid Systematic Review (Dr. Carl Juneau) I first wrote about COVID-19 on March 13. Since then, in response to the pandemic, countries implemented a range of interventions urgently, often without a clear picture of their effectiveness and cost-effectiveness. What is the evidence? When we started our search, we found that it looked slim. Indeed, earlier reviews have concluded that the evidence for these interventions is lacking (except for hand washing and face masks). But those reviews included only randomized trials (considered high-quality evidence).
In our systematic review, we included a broad range of study designs to summarize the evidence of all levels of strength and guide urgent decision making. In this context, we believe that evidence of lower quality is better than no evidence at all. Especially if it can help avoid unnecessary damage to the economy and other harms.
For example, a popular intervention is school closures, which currently affect over 1.5 billion (almost 90%) of the world's students (WHO, 2020). In the US, this has been estimated to cost $10 to $47 billion for 4 weeks (Lempel et al. 2009). Contrast that with contact tracing and case isolation, which as we saw above, has been estimated to be 4,363 times more cost-effective for H1N1 influenza ($2,260 vs. $9,860,000 per death prevented).
Note that preprints are not peer reviewed, so these conclusions may need further validation
Continued here
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